【 sulfobutylbetacyclodextrin sodium 】 Product features (Use description) :
Sulfobutylbetacyclodextrin sodium, also known as sulfobutylether betacyclodextrin sodium salt, sulfobutylbetacyclodextrin sodium is a sulfonated modified sodium salt of betacyclodextrin, also known as thiobutylether betacyclodextrin sodium, is an anionic highly water-soluble cyclodextrin derivative, which can be well incorporated with drug molecules to form non-covalent complexes. It can improve the stability, water solubility, safety, reduce renal toxicity, relieve hemolytic, control drug release rate, cover up bad odor and so on.
[Route of administration] : injection drug, oral drug, nasal drug, eye drug, has special affinity and inclusion for nitrogen-containing drugs.
【 sulfobutylbetacyclodextrin sodium 】 Product properties:
1. Solubility:
Neutral, positive and negative apis can be effectively combined with sulfobutylbetacyclodextrin, so that the different solubility of the compound in the raw potion can be increased by 10 to 25,000 times.
2, convenient drug delivery:
Sulfobutylbetacyclodextrin has excellent biocompatibility and can be administered by injection, oral, eye, nose, topical and inhalation.
3, good security:
It is usually rapidly and completely eliminated from the kidneys after administration. In vitro and in vivo studies of acute, subacute, and chronic toxicity provided safe data and approved pharmaceutical formulations for human use.
4, good stability:
The interaction with sulfobutylbetacyclodextrin provides a beneficial protective environment for the API in its lipophilic chamber, while the hydrophilic surface provides excellent water solubility and stability. |