(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine, 

commonly abbreviated as S-DMAA, CAS No. 132335-44-5, 

is an important chiral intermediate used in the synthesis of Duloxetine hydrochloride. 

It is also known as (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol. 

Strict chiral control is critical for downstream API production. 

We are a professional manufacturer and supplier of this Duloxetine intermediate, supporting small trial orders, pilot scale and commercial bulk quantities. 

We can provide COA, HPLC, Chiral HPLC report, TDS and SDS for your R&D and registration work. 

Sample service is available upon request.

Specification

• Purity (HPLC): ≥99.5%

• Water Content (KF): ≤0.5%

• Melting Point: 78–80 ℃

• Max. single impurity：≤0.2%
  

• D-Isomer:≤0.5%

Application

S-DMAA (CAS 132335-44-5) is the key chiral precursor for manufacturing Duloxetine hydrochloride, a serotonin-norepinephrine reuptake inhibitor API. It is widely used by pharmaceutical R&D labs, CRO companies and API manufacturers for process development and commercial production of Duloxetine.

FAQ

Q1: What is CAS 132335-44-5 used for?

A: CAS 132335-44-5 (S-DMAA) is a key chiral intermediate for Duloxetine hydrochloride API synthesis.

Q2: What is S-DMAA?

A: S-DMAA is the short name of (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine, CAS 132335-44-5.

Q3: Can you provide sample of S-DMAA (132335-44-5)?

A: Yes, we support lab samples for quality testing. Please contact us for sample quotation and shipping arrangement.

Q4: What documents can you offer for S-DMAA?

A: We can supply COA, HPLC report, chiral HPLC, TDS and SDS.

Q5: What is the chiral purity of your 132335-44-5?

A: Our S-DMAA can reach ≥99.5% ee, suitable for high-standard API process.

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